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East Kalimantan has a very high plant diversity of the various ethnic Dayak who has knowledge of medicinal plants for generations to cope with the health of the surrounding community. One of the plants is Tabar Kedayan (Aristolochia foveolata Merr.), Which is empirically efficacious as an antidote (anti-venom). But not scientifically confirmed, this is due to the small number of studies on the content of secondary metabolites and bioactive compounds contained in plant Tabar Kedayan. This study aims to determine the security level of the root extract Tabar Kedayan, namely the acute toxicity test to determine the LD5. Based on the results of research and analysis of the results of the acute toxicity test Tabar kedayan ethanol extract of the roots, it can be concluded, that the LD50 value of the ethanol extract of the roots of Tabar kedayan is 10.25 g / kg. body weight of mice and categorized slightly toxic.
Keywords: Tabar Kedayan, Aristolochia foveolata Merr., Accute toxicity
